Dr. Manzanares was born in Barcelona and graduated in Medicine and Surgery from the Autonomous University of Barcelona in 1982. He resides in Barcelona and specializes in family medicine, integrating homeopathy and reflexology with conventional medicine. His reflexology research in neuro-physiology at University Hospital Vall D’Hebron and Hospital Sagrado Corazon, Barcelona spans 3 decades and documentation of 70,000 clinical cases.Dr. Manzanares' career is divided between medical care, teaching and lecturing. Traveling to the U.S. numerous times a year, he teaches his continuing education course, “The Manzanares Method^TM and Science of Reflexology”, which is based on his research principles and methods.

Research in the field of reflexology began for Dr. Manzanares with a focus on three primary goals that he accomplished: to explain the neuro-physiological basis (the nervous system pathways for reflexology); to determine specific anatomical location of the reflex areas of feet (developing precision mapping of the foot-to-body connection over 27 years on 70,000 clinical cases); and finally, to establish reflexology protocols for pathologies.

Further research includes biopsy studies to determine the characteristics of the tissue in the feet for areas referred to as ‘deposits’; crossed reflex representation in the feet to bring precision and correction to the Fitzgerald zone theory, research using reflexology for ADHD and research concluding the beneficial effects of reflexology for hypertension. 

In his books, Reflexology Research Handbook (2017) and Reflexology Maps and Depostis (2018), Manzanartes Textbook of Reflexology" (2020), Dr. Manzanares diagrams his investigations in elaborate detail, illustrates the reticular core of the brain stem as the common pathway from the feet to internal organs of the autonomic nervous system and charts his reflexology protocols with dosaging of pressure, duration and frequency.